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filingDate 2002-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd8477377afb99857f5fd78b3f89757e
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publicationDate 2002-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2002160034-A1
titleOfInvention Use of occlusion device for the local delivery of biologically active DNA therapeutic compounds for treating aneurysms and use therefor
abstract The invention relates to a method for the sustained endovascular treatment of aneurysms, such as intracranial or for closing any body lumen, such as vascular lumen or other using an occlusion device for the local delivery of biologically active DNA therapeutic molecules. The invention also relates to a method for a rapid preparation of the artificial occlusion device to be coated shortly before or during the clinical procedure. A subsequent step in the method of treatment involves introducing at an aneurysm site or inside a vessel a slow-releasing, biologically active DNA molecule-leaching device. The device releases a biologically active DNA molecule at the aneurysm site for stimulating neointima formation and for increasing neointima thickness. The neointima formation fills the aneurysm and the biologically active DNA molecule released in the aneurysm is absorbed by surrounding tissues of the aneurysm for providing long-term treatment of the aneurysm preventing recanalisation.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008249511-A1
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014012189-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11510680-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7396540-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11510681-B2
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