http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002158017-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-366 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2002-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afe95b7f2647d5b57ae7d5afdeb7bc50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b6e74e60c315427154affb3c36a8eef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e70c4209b795d679aba9b3cb43115d3 |
| publicationDate | 2002-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2002158017-A1 |
| titleOfInvention | Method for high resolution liquid chromatographic separation of homoduplex and heteroduplex DNA |
| abstract | Mixtures of dsDNA fragments are separated by Matched Ion Polynucleotide Chromatography (MIPC) using an isocratic mobile phase to elute polynucleic acid from an MIPC column. The use of isocratic elution conditions provides a marked improvement in the separation of dsDNA fragments compared to gradient elution conditions. Isocratic elution can also be used to effect an improved separation of heteroduplex and homoduplex mixtures when the chromatography is performed under partially denaturing conditions. In addition, dsDNA fragments are bound to the stationary phase under isocratic conditions until a solvent concentration is reached which releases fragments of a particular base pair length range. This separation process is different from the equilibrium partitioning process observed under gradient elution conditions. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005011836-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7125492-B2 |
| priorityDate | 1997-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 361.