abstract |
2,3-Dihydrobenzofuran derivatives of general formula n n n wherein R 1 represents a hydrogen atom or an acyl group; R 2 , R 3 and R 4 represent a hydrogen atom, a lower alkyl group or a lower alkenyl group; R 5 and R 6 combine to form a cycloalkyl group or a saturated heterocyclic group containing one or more oxygen atoms or sulfur atoms, provided that R 2 and R 3 can not simultaneously represent a t-butyl group, or optically active isomers or pharmaceutically acceptable salts thereof are useful as therapeutic or prophylactic agents for various renal diseases and as organ preservatives. |