| abstract |
The invention features the analysis of Sal2 nucleic acids and proteins for diagnosing and treating patients having proliferative disorders, including cancer, involving mutations in a Sal2 gene and encoded protein. The invention also includes transgenic and knockout mice including Sal2 nucleic acids or proteins and mutants thereof. Furthermore, the invention features a method of killing cells carrying a Sal2 alteration using a T-HR mutant. |