| abstract |
The invention relates to new compounds of general formula I n n n or the pharmaceutically acceptable salts thereof, wherein n X=N—R 3 or CH—R 4 , n Y=CH 2 or (CH 2 ) 2 , n Z=O or H 2 ; n and R 1 , R 2 , R 3 , R 4 and Ar n have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin) antagonists. |