| abstract |
A compound represented by the formula: n n n wherein ring M is a heterocyclic ring wherein n —X═Y< n is one of —N═C<, —CO—N< or —CS—N<; n R a and R b are bonded to each other to form Ring A, or they are the same or different and represent, independently, a hydrogen atom or a substituent on the Ring M; n Ring A and Ring B represent, independently, an optionally substituted homocyclic or heterocyclic ring, with the proviso that at least one of them is an optionally substituted heterocyclic ring; n Ring C is an optionally substituted homocyclic or heterocyclic ring; n Ring Z is an optionally substituted nitrogen-containing heterocyclic ring; and n n is an integer from 1 to 6, or a salt thereof has a tachykinin receptor antagonistic activity in vitro, and is useful for preventing or treating depression, anxiety, manic-depressive illness or psychopathy. |