| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01L27-0248
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-06 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L27-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54 |
| filingDate |
2001-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e1aaa8a5c26fe216caa96552025075c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7436e2d2b44668ba91e5ba009af0ce3b |
| publicationDate |
2002-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2002115867-A1 |
| titleOfInvention |
Imidazolyl/benzimidazolyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension |
| abstract |
Compounds characterized generally as imidazolyl/benzimidazolyl-terminated alkylamino ethynyl alanine amino dial derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of Formula I n n n wherein A is selected from CO and SO 2 ; wherein X is selected from oxygen atom and methylene; wherein B is selected from imidazolyl and benzimidazolyl groups; wherein R 1 is selected from hydrido, methyl, ethyl, isopropyl and n-propyl; wherein R 2 is phenylmethyl; wherein each of R 3 and R 5 is hydrido; wherein R 4 is selected from n —(CH 2 ) q —C≡C—V n wherein V is selected from hydrido and methyl; wherein R 6 is cyclohexylmethyl; wherein R 7 is selected from isobutyl, cyclopropyl and cyclopropylmethyl; wherein q is a number selected from zero through three, inclusive; and wherein n is a number selected from zero through three, inclusive; or a pharmaceutically-acceptable salt thereof. |
| priorityDate |
1992-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |