http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002115071-A1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34
filingDate 2001-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b983e86964acc5d2fd698f1ed2a104c
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publicationDate 2002-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2002115071-A1
titleOfInvention High throughput assay for monitoring polycation or polyanion molecular weight, degradation or synthesis
abstract A method of testing an agent for its potential at modulating induction of a molecular weight change of a first polyion is disclosed. The method is effected by (a) subjecting the first polyion to conditions under-which the first polyion undergoing the molecular weight change in a presence, in an absence or under several different concentrations of the agent; (b) interacting the first polyion with a second polyion having an opposite charge, the second polyion being fluorescently labeled; (c) providing reaction conditions so as to allow molecular weight discriminative interaction between the first polyion and the second polyion; and (d) employing a fluorescence polarization assay for determining a modulating effect of the agent on the induction of the molecular weight change of the first polyion.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006025625-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110041522-A
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