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publicationDate 2002-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2002111644-A1
titleOfInvention Fluid jet PMR
abstract Devices and methods for performing myocardial revascularization using fluid jets. Devices can include a pressurized fluid source coupled through fluid supply lumens to a distal-most nozzle disposed on the distal end of the catheter. Some devices have separate myocardial revascularization catheters disposed within guide catheters, while other devices have unitary devices including a generally steerable myocardial revascularization catheter shaft. Preferred embodiments include a distally disposed control valve. One valve is controlled using an electrically actuated device, another valve is controlled using a low-pressure control fluid, while yet another device valve is controlled using an axially slidable activation wire. The fluid valve can include a biasing spring to shut the valve and preclude fluid flow, with the bias opposed by a user-applied fluid, mechanical, or electrical force. One device includes a radially expandable distal catheter portion, which expands under pressure to present a significantly larger distal profile. The inflated distal region may be forced against a heart chamber wall, and can provide a larger surface area and improved seal. One catheter includes an intermediate expandable tubular anchor portion. Fluid used in the devices can include saline, revascularization enhancing therapeutic substances, angiogenic promoting substances, and radiopaque contrast media, all of which can be injected at the same time.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010085292-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009150594-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8034065-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004122360-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013158544-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2009338144-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010191222-A1
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