http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002111348-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 2001-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddb27c81543e442ee77b4bdff92d8d0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffbd682066d836f2a474a032b906b15d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_799da2a84b3aa9ba237457e0414e37f4 |
| publicationDate | 2002-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2002111348-A1 |
| titleOfInvention | Substituted oximes and hydrazones as neurokinin antagonists |
| abstract | Compound represented by the structural formula n n n or a pharmaceutically acceptable salt thereof, wherein: n a is 0-3; n b, d and e are 0-2; n R is H, alkyl, F or —OR 6 ; n A is an optionally substituted oxime or hydrazone; n d is not 0 and X is a bond, —C(O)—, —O—, —NR 9 —, —S(O) e —, —N(R 6 )C(O)—, —C(O)N(R 6 )—, —OC(O)NR 6 —, —OC(═S)NR 6 —, —N(R 6 )C(═S)O—, —S(O) 2 N(R 6 )—, —N(R 6 )S(0) 2 —, —N(R 6 )C(O)O—, —OC(O)— or —N(R 6 )C(O)NR 7 —; or d is 0 and X is a bond or —NR 6 —; n T is H, aryl, heterocycloalkyl or heteroaryl; n Q is phenyl, naphthyl or heteroaryl; n R 6 is H, alkyl, hydroxyalkyl, alkoxyalkyl, phenyl, and benzyl; n R 9 is R 6 or —OR 6 n R 6a , R 7a , R 8a and R 9a are H or alkyl; n Z is a nitrogen-containing heterocyclo group, e.g., piperidinyl, substituted by a heterocyclo- or heterocycloalkyl group; n wherein phenyl, benzyl, aryl, heterocycloalkyl, heteroaryl and cycloalkyl groups are optionally substituted; methods of treating diseases such as asthma, cough, bronchospasm, depression, emesis, imflammatory diseases, and gastrointestinal disorders with said compounds, and pharmaceutical compositions comprising said compounds are disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7964181-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010035821-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009264388-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009069224-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8114844-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8580746-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007260040-A1 |
| priorityDate | 1998-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 913.