| abstract |
Dibenzofluorene derivatives having a formula selected from the group consisting of n n n and salts thereof have antitumor activity. At least one of R 1 -R 13 in formula (I) or R 1 -R 12 in formula (II) is —R 14 Z. R 14 is a substituted or unsubstituted amino or amido group having from 1-12 carbon atoms, and Z is a substituted or unsubstituted heterocyclic group having from 1-12 carbon atoms. The remainder of R 1 -R 13 in formula (I) or R 1 -R 12 in formula (II) are independently selected from the group consisting of hydrogen, hydroxyl, halogen, nitro, substituted or unsubstituted amino or amido groups having from 1-12 carbon atoms, and alkyl groups having 1-12 carbon atoms. |