http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002102211-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-281 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4088 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-055 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055 |
| filingDate | 2001-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda8d05a3268bfe5ca83facd4407268a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ab38f724f4d915b4eff320e33d00e54 |
| publicationDate | 2002-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2002102211-A1 |
| titleOfInvention | Use of magnetic resonance imaging in diagnosis of membrane fluidity-related disorders |
| abstract | The invention relates to methods of diagnosing membrane fluidity-related disorders, or predispositions to membrane fluidity-related disorders, in a subject such as a human patient or an animal, e.g., an animal model of a human disorder. In general, the method includes acquiring a first proton relaxation measurement for a selected region of the brain in a magnetic resonance imaging (MRI) procedure; administering to the subject a challenge that alters physical properties or chemical composition of cell membranes in the brain of the subject; acquiring a second proton relaxation measurement for the selected region of the brain in an MRI procedure; and detecting any difference, e.g., an increase or decrease, between the first proton relaxation measurement and the second proton relaxation measurement, wherein a difference indicates a membrane fluidity-related disorder. The invention also includes methods of assessing the effectiveness of treatments or drugs, e.g., drug candidates in an animal model, for such disorders. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8200508-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008059244-A1 |
| priorityDate | 2000-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.