abstract |
An improved combination microporous membrane and solid support for use in micro-analytical diagnostic applications is disclosed. Specifically, a multi-cell substrate useful for carrying a microarray of biological polymers on the surface thereof including a multi-cell substrate having a porous membrane formed by a phase inversion process effectively attached by covalent bonding through a surface treatment to a substrate that prepares the substrate to sufficiently, covalently bond to the microporous membrane formed by a phase inversion process such that the combination produced thereby is useful in microarray applications and wherein the porous nylon multi-cell substrate is covalently bonded to a solid base member, such as, for example, a glass or Mylar microscope slide, such that the combination produced thereby is useful in microarray applications. Apparatus for fabricating a multi-cell substrate is also disclosed. |