Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55511 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 |
filingDate |
2001-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6306e877f2c7c11de46dbf01d154d32b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0977bf162453d1ea633c997d97c806e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3c23280450fe64d6be6b01598eb84d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efa6f0e1398be73d597e79d5b7f7a121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed44d2c647a31d0cfed5c8db25f0fd09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cccef132687efaa9c7c5c8f09587d3a |
publicationDate |
2002-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2002086027-A1 |
titleOfInvention |
Composition and method for enhancing immunological memory response |
abstract |
A strategy for inducing immune T lymphocytes to respond in such a fashion to their target antigen at first exposure so as to enable them to mount a response of greater magnitude upon any subsequent exposure to the same target is provided. The strategy involves exposure of T cells or animals being immunized to the commonly used phosphodiesterase inhibitor drug, pentoxifylline (POX/PF/Trental), during immune priming. Evidence is provided showing that such exposure leads to enhancement of immune T cells responses upon re-exposure. The strategy is relevant and useful for increasing the efficiency of vaccinations. |
priorityDate |
1998-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |