abstract |
The present invention concerns novel, naturally occurring splice variants of the TNF-related apoptosis inducing ligand (TRAIL). Provided are coding nucleic acid sequences and the polypeptides encoded thereby, vectors and host cells containing said nucleic acid sequences and antibodies reactive with said polypeptides. The invention also concerns pharmaceutical compositions for the treatment of certain diseases, comprising the nucleic acid sequences, the amino acid sequences, the expression vectors or the antibodies. |