Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2836 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2839 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2842 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70542 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
filingDate |
2001-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76afe41ea2c1a80964e4929e18741d99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2ac68d6832dfadae32ff03fc4832049 |
publicationDate |
2002-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2002041874-A1 |
titleOfInvention |
Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists |
abstract |
Antagonists of α4 integrin/α4 integrin ligand adhesion, which inhibit the biological effects of such adhesion are described and methods for their use are detailed. Such antagonists are useful in suppressing bone destruction associated with multiple myeloma. The homing of multiple myeloma cells to bone marrow and their α4 integrin-dependent release of bone-resorbing factors, resulting in bone destruction in patients with multiple myeloma, is inhibited. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7618630-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8026230-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1565193-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1565193-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005267037-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11376332-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010183599-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685954-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002159998-A1 |
priorityDate |
1998-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |