Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
filingDate |
2001-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd7e031dafa631d6dc667522e9c5c973 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e73e7b8888f13171eb354f85efbcada http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a1aad0daa25614f633d43b2c9f0f437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3c6ad676cc0ca4f19e85321a39b81fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09c54c804a5d6e584e5861b99cb56548 |
publicationDate |
2002-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2002040051-A1 |
titleOfInvention |
Solid dispersion of ipriflavone for oral administration and its manufacturing methods |
abstract |
This invention relates to an ipriflavone-containing pharmaceutical agent for oral administration with improved bioavailability, wherein ipriflavone is solid-dispersed in the presence of a water-soluble polymer, an absorption fortifier, and an excipient while the crystal of said pharmaceutical agent is prepared in an amorphous form at the same time so that said ipriflavone can be enclosed in said water soluble polymer, and thus even a little amount as well as lower number of dosage of said ipriflavone pharmaceutical agent can increase the effective blood concentration of said ipriflavone pharmaceutical agent and the solubility for the body fluid in the gastrointestinal tract, thereby remarkably improving the bioavailability of said agent which can much reduce both the uncomfortableness in its usage and the burden that is usually laid on the gastrointestinal tract by a heavy dose and also increase the stability during a long-term storage. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8974823-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009062231-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009060943-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007148232-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007141143-A1 |
priorityDate |
2000-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |