Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-19 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate |
2001-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3cc56eaf64f840c1e23b8a117b7b6a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41424fefe02821e242f46441416f4e71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f861fa5b65e888fa2180f1a10f353456 |
publicationDate |
2002-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2002039791-A1 |
titleOfInvention |
Methods and compositions for inhibiting thrombin generation at the surface of cells |
abstract |
The present invention provides methods for preventing the generation of active thrombin on the surface of cells. The present methods are based upon the surprising discovery that expression or activation of an ER resident chaperone protein in a cell inhibits the generation of thrombin on the surface of the cell. Accordingly, expressing or activating an ER resident chaperone protein can be used to treat or prevent any of a number of thrombotic diseases. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003008272-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02095061-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7306905-B2 |
priorityDate |
2000-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |