| abstract |
A triterpene derivative useful for the treatment of hepatic disorders is disclosed. This compound comprises as an active ingredient a triterpene derivative represented by the following formula (I) or a salt thereof: n n n wherein R 1 represents a hydroxyl group, arylmethyloxy, lower alkoxy, or lower alkanoyloxy, R 2 represents lower alkyl, lower alkenyl, —CH 2 OR 5 , formyl, —COOR 6 , or —CH 2 N(R 7 )R 8 , or R 1 and R 2 may combine with each other to form —O—C(R 9 )R 10 —O—CH 2 —, R 3 and R 4 , which may be the same or different represent a hydrogen atom, a hydroxyl group, lower alkyl, lower alkenyl, aryl, hydroxymethyl, —N(R 11 )R 12 , formyl, —COOR 6 , or —OR 13 , or R 3 and R 4 may combine with each other to form oxo, hydroxyimino, or alkylidene and X represents O, CH 2 , or NH. |