abstract |
Method for the prevention or treatment of pruritus with anti-pruritic compounds is provided. n The compounds of formulae I, II, IIA, III, IIIA, IV and IVA have the structure: n n n wherein n R 1 , R 2 , R 3 , R 4 ; and n X, X 4 , X 5 , X 7 , X 9 ; n Y, Z and n are as described in the specification. |