http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002006380-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
filingDate | 2000-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdec51b733a4b1e80882f3a10db26980 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_555eae88ff09500f5d27ee551dd7dcdf |
publicationDate | 2002-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2002006380-A1 |
titleOfInvention | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them |
abstract | The invention concerns pyrrole derivatives of general formula (I) wherein: R 1 is CONH 2 , CN, carboxy, alkyloxycarbonyl, or acyl; R 2 is a H atom, a halogen atom, a CN, alkyl, alkyoxy, alkenyl or trihalogenomethyl radical; R 3 is a H atom or a halogen atom, or an alkyl or OH radical; Het is pyridyl, pyridyl N-oxide or thiazolyl; R 4 is a H atom or a halogen atom, an alkylthio or alkyloxy radical; and R 5 is a H atom, or a hydroxy or alkyloxy radical; provided that when R 3 , R 4 and R 5 are H atoms and Het is a pyridin-2-yl radical, then R 1 cannot be acetyl or methyloxycarbonyl and R 2 is a H atom, or R 1 cannot be propionyl and R 2 methyl, the C 1 -C 4 alkyl and C 2 -C 4 alkenyl radicals being linear or branched, as the case may be in the form of stereoisomers or their mixtures and/or their salts when they exist. Said derivatives are particularly useful for treating and preventing diseases wherein are involved herpes family viruses and/or wherein are involved cytokines including TNFα. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011184011-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012015972-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105753862-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105753864-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018174281-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8748452-B2 |
priorityDate | 1998-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 320.