abstract |
The subject of the invention is the products of formula (I): n n n in which either R 1 represents halogen, hydroxyl, (C 1 -C 8 ) alkyloxy or (C 1 -C 12 ) acyloxy, and R 2 represents halogen or hydrogen, or R 1 and R 2 form together a double bond, Z is chosen from optionally substituted (C 1 -C 8 ) alkylthio, optionally substituted arylthio, (C 1 -C 8 ) alkyloxy, halogen, cyano, mercapto, thiocyanato and (CH 2 ) 0-1 —CO 2 H, optionally esterified, Y represents hydrogen or methyl, the dotted line in position 1-2 or 5-6 optionally representing a second bond, as well as their addition salts, their preparation process, the intermediates of this process and the pharmaceutical compositions containing them. |