| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-285
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-287
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-261
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-366 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-36 |
| filingDate |
2001-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fd6b4c82264565493b6387fdec026d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a0e5a88626910b5e96c49f43c0041f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab5aaf72ed158479a44d5eb14cf0e906
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a21d50d8ec0c42f793b06a792a86c488
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afe95b7f2647d5b57ae7d5afdeb7bc50 |
| publicationDate |
2001-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2001051715-A1 |
| titleOfInvention |
Chromatographic method for RNA stabilization |
| abstract |
The instant invention provides a method for stabilizing an RNA molecule against degradation comprising applying a solution to a separation medium having a non-polar separation surface in the presence of a counterion agent, wherein the solution comprises the RNA molecule and an agent capable of catalyzing the degradation of RNA; eluting the RNA molecule from the separation medium by passing through the separation medium a mobile phase containing a concentration of organic solvent sufficient to elute the RNA molecule from the separation medium, where the elution is conducted under conditions that result in a substantial separation of the RNA molecule from the agent capable of catalyzing the degradation of RNA; and collecting an eluant fraction containing the RNA molecule that is substantially free of the agent capable of catalyzing the degradation of RNA. In a preferred embodiment the method is performed under conditions that are substantially free of multivalent cations. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103717285-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009143234-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10392713-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9896682-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9816189-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10274465-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004027023-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004027023-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11136675-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8507197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014090453-A1 |
| priorityDate |
2000-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |