| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2400-179 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23C9-1234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23C9-123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 |
| filingDate |
2001-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_659a17245a03f0081518449c9ebe5c3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_374efeb8a4ca8e4d41deabe963e020d4 |
| publicationDate |
2001-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2001049115-A1 |
| titleOfInvention |
Vitro model for gastrointestinal inflammation |
| abstract |
An in vitro test for testing the immunomodulatory especially anti-inflammatory or pro-inflammatory effect of a test material comprises placing a microporous support having a monolayer of epithelial cells therein in contact with a nutrient medium in a culture well. Cells of the immune system such as peripheral blood mononuclear cells are introduced into the medium and a test material is also introduced into the nutrient medium. A change in an immunological marker, especially a cytokine, particularly TNF&agr; or IL-8 in response to the test material is determined. The test material may be a strain of Lactobacillus or Bifidobacterium or other material which may be a probiotic. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010068719-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109116033-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006035301-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010030655-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10689719-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010183559-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005073400-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008145341-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011269165-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005073400-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9771624-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9176116-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2735873-A1 |
| priorityDate |
2000-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |