http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2001047021-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94ff2d78578d95d1e8d3a2233c76188d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2001-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61f58f5edd62a553088c40254f75f558 |
| publicationDate | 2001-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2001047021-A1 |
| titleOfInvention | Cancer treatment |
| abstract | This invention is a method of treating cancer, including carcinomas and sarcomas through the administration of a pharmaceutical composition containing a tetra-substituted benzimidazole carbamate. The tetra-substituted benzimidazole carbamate is selected from the group consisting of: n n n wherein X, Y, Z and A are independently selected from the group consisting of bromo, fluoro, chloro, iodo and alkyl of less than 4 carbon atoms or alkoxy of less than 4 carbon atoms; and R is hydrogen, alkylaminocarbonyl wherein the alkyl group has from 1 to 4 carbon atoms or an alkyl group of from 1 to 8 carbon atoms and R 1 is aliphatic hydrocarbon of less than 7 carbon atoms; or its pharmaceutically acceptable salts; or prodrugs thereof. Preferably R 1 is an alkyl group of less than 3 carbon atoms and X,Y, Z and A are halogen. Most preferred is 2-methoxycarbonylamino-4,5,6,7-tetrafluorobenzimidazole. The tetra-substituted benzimidazole carbamate and pharmaceutical compositions containing them are claimed herein. X,Y,Z and A are preferably electron withdrawing groups. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005004026-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7592143-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107102141-A |
| priorityDate | 2000-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 574.