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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K29-00
filingDate 2001-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbd9f075ce12a214ba9e789c898d46f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8d44c0187c54f7a163ee4ae53df3615
publicationDate 2001-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2001042520-A1
titleOfInvention Method for producing model animals for itching induced by disruption of cutaneous barrier function
abstract The present invention provides itching model animals usable for evaluating the therapeutic effect of medicines, medicinal compositions, external preparations for the skin, etc. on itching induced by hypofunction of cutaneous barrier and also for evaluating the effect in improving the barrier function of the skin weakened and converted to be itchy by an external preparation for the skin or a cosmetic. The present invention also provides a method for producing such animals. n Itching symptoms are realized by degreasing the glabrous skin of each of small test animals with an organic solvent and then treating the skin with water to induce a lesion of the skin by the disruptions of the barrier function without inflammation.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004245477-A1
priorityDate 2000-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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