| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate |
1999-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4c7bb8990258b1f3c1bbd9a5a6c3c48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f5182d866f84b5b03ef9061fa41fbd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69e6c1876fa75cb8064cc109273de0c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22bccd245726c25a9c74d322448599f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2765208a57446585b9f9bc22291d3695
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58f2d547c14c0ee26737cd86eed349b2 |
| publicationDate |
2001-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2001027182-A1 |
| titleOfInvention |
Chaperone suppression of ataxin-1 aggregation and altered subcellular proteasome localization imply protein misfilind in sca1 |
| abstract |
The present invention provides a novel method for treating neurodegenerative disease in mammals. This method involves the introduction of a therapeutic effective amount of a chaperone, a chaperone-like-compound or a compound which increases proteasome activity into the neurological system of the mammal. There is also a novel method for screening for compounds having chaperone-like activity or having activity to increase proteasome activity. The screening works in either cultured cells or animal models. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008206843-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7445904-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109152350-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8034766-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8431526-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004064844-A1 |
| priorityDate |
1998-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |