| abstract |
The present invention relates to microdroplets of a solution comprising a solvent having a boiling point of 150° C. or above, a surface tension of 30 dynes/cm or above, and a viscosity of 0.015 g/(cm)(sec). Such microdroplets are useful for the synthesis of chemical species, particularly biopolymers such as oligonucleotides and peptides, as well as arrays of chemical species. Preferably, the solvent has the formula (I): n n n wherein n A=O or S; n X, O, S or N(C 1 -C 4 alkyl); n Y=O, S, N(C 1 -C 4 alkyl) or CH 2 ; and n R=C 1 -C 20 straight or branched chain alkyl. |