http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2001011089-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14
filingDate 2001-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddb27c81543e442ee77b4bdff92d8d0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_799da2a84b3aa9ba237457e0414e37f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffbd682066d836f2a474a032b906b15d
publicationDate 2001-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2001011089-A1
titleOfInvention Substituted oximes and hydrazones as neurokinin antagonists
abstract Compound represented by the structural formula n n n or a pharmaceutically acceptable salt thereof, wherein: n a is 0-3; n b, d and e are 0-2; n R is H, alkyl, F or —OR 6 ; n A is an optionally substituted oxime or hydrazone; n d is not 0 and X is a bond, —C(O)—, —O—, —NR 9 —, —S(O) e —, —N(R 6 )C(O)—, —C(O)N(R 6 )—, —OC(O)NR 6 —, —OC(═S)NR 6 —, —N(R 6 )C(═S)O—, —S(O) 2 N(R 6 )—, —N(R 6 )S(O) 2 —, —N(R 6 )C(O)O—, —OC(O)— or —N(R 6 )C(O)NR 7 —; or d is 0 and X is a bond or —NR 6 —; n T is H, aryl, heterocycloalkyl or heteroaryl; n Q is phenyl, naphthyl or heteroaryl; n R 6 is H, alkyl, hydroxyalkyl, alkoxyalkyl, phenyl, and benzyl; n R 9 is R 6 or —OR 6 n R 6a , R 7a , R 8a and R 9a are H or alkyl; n Z is a nitrogen-containing heterocyclo group, e.g., piperidinyl, substituted by a heterocyclo- or heterocycloalkyl group; wherein phenyl, benzyl, aryl, heterocycloalkyl, heteroaryl and cycloalkyl groups are optionally substituted; methods of treating diseases such as asthma, cough, bronchospasm, depression, emesis, imflammatory diseases, and gastrointestinal disorders with said compounds, and pharmaceutical compositions comprising said compounds are disclosed.
priorityDate 1998-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 878.