Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6818 |
filingDate |
1998-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_391741f8fb5545eee8ce66649301635d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27d07def577bca6f7d52c1290a73491e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a589ce8466fa50635e765eed12a6805 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73f5d9dfb0ffa05e35bd47a90c737517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f6cb458e0ddff1770219652a2c15a7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92af5c836e8bda83943321371e4218d3 |
publicationDate |
2001-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2001009760-A1 |
titleOfInvention |
Oligonucleotide probes bearing quenchable fluorescent labels, and methods of use thereof |
abstract |
Methods are provided for reducing background signals encountered in nucleic acid hybridization assays and other assays that involve hybridization of a labeled oligomer to its complement. The method is premised on the significant reduction of signal generation that occurs when a quenchable dye-labeled oligomer forms a hybrid complex. In addition, a method is provided for enhancing the detectable signal emitted from an amplification multimer hybridized to an oligomer probe to which a quenchable dye has been conjugated through a linker such that the emission from the dye is not quenched upon hybrid complex formation. Novel oligonucleotide probes are also provided that comprise an oligomer to which has been directly or indirectly through a linker a quenchable dye. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004132061-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004063137-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8865414-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8394944-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010212040-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011311966-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7429655-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8916503-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006147937-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008103296-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109865143-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005064435-A1 |
priorityDate |
1997-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |