http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2001005762-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C201-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-50 |
| filingDate | 2000-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8178cd9e37a8a9700fe8c2aba2fd30c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dce74b493bd46c1b0698ef2b940833ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da07cfcb5b1fbbda6d0974ff55e39f38 |
| publicationDate | 2001-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2001005762-A1 |
| titleOfInvention | Methods for producing and separating erythro- and threo-2-hydroxy-3-nitrobutanoic acid compounds |
| abstract | The present invention provides a method of producing easily and in a high yield a threo-2-hydroxy-3-nitrobutanoic acid compound or a mixture of a threo- and an erythro-2-hydroxy-3-nitrobutanoic acid compounds, this mixture having an erythro compound:threo compound ratio of about 1:1, which method includes reacting, in a solvent, a 2-hydroxy-3-nitrobutanoic acid compound having the formula (I) n n n wherein R is optionally substituted alkyl or optionally substituted aryl, with not less than 1 equivalent of a base to isomerize (i) the erythro compound into the threo compound, or (ii) the threo compound into the erythro compound, and a method for separating the erythro and the threo compounds easily and in a high yield. The separation method includes reacting the mixture of threo- and erythro-compounds with not more than 1 equivalent of potassium carbonate per threo compound in a solvent. According to the method of the present invention, useful pharmaceuticals can be produced easily in a high yield. |
| priorityDate | 1999-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.