| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a012146da9381dd2fd222191994e23da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6acd6d98a9ae96f5bd0e454990838d0a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2025-0293
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2025-0063
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M27-006 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M25-0102 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M25-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M25-01 |
| filingDate |
2018-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2023-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dd4c73706780ada830086b6d93e2fa1 |
| publicationDate |
2023-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11541005-B2 |
| titleOfInvention |
Systems and methods for enhanced distribution of a biologic agent within the brain and spinal cord |
| abstract |
Aspects herein relate to systems and methods for delivery of biologic agents to the central nervous system. In various embodiments, a method of administering a therapeutic agent to the central nervous system (CNS) is included. The method can include injecting a therapeutic agent into a first cerebrospinal fluid (CSF) region of the subject. The method can further include establishing fluid communication between a fluid reservoir and a second cerebrospinal fluid (CSF) region of a subject, the fluid having a hydraulic pressure at or above an intracranial pressure. The method can further include infusing a hyperosmotic fluid systemically. Other embodiments, including kits and systems are also included herein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11723865-B2 |
| priorityDate |
2017-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |