Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef681a48b833f8ddca6983f43f4d0bb9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-10 |
filingDate |
2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9a704d65d77c54ff144d0765b2dbb89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d48a53b3b16630d8d6e1dfd75b71572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_244dc4b39c6ade3dad290f70110262a9 |
publicationDate |
2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11530428-B2 |
titleOfInvention |
Nucleic acids encoding fungal cellobiohydrolases for expression in yeast |
abstract |
The present invention provides for heterologous expression of polypeptides encoded by wild-type and condon-optimized variants of cbh1 and/or cbh2 from the fungal organisms Talaromyces emersonii (T. emersonii), Humicola grisea (H. grisea), Thermoascus aurantiacus (T. aurantiacus), and Trichoderma reesei (T. reesei) in host cells, such as the yeast Saccharomyces cerevisiae. The expression in such host cells of the corresponding genes, and variants and combinations thereof, result in improved specific activity of the expressed cellobiohydrolases. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems. |
priorityDate |
2008-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |