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filingDate 2021-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24e769c2ba486781599bab2da2de6056
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publicationDate 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11529626-B2
titleOfInvention Temperature controlled valves for paper-based microfluidic systems
abstract The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.
priorityDate 2016-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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