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filingDate 2017-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11504512-B2
titleOfInvention Method of fabricating microneedle patches
abstract In the preferred embodiment, a method of making microneedles comprises i) providing a microneedle template ( 300 ) having a plurality of microneedles cavities ( 360 ) on one surface, ii) preparing a casting solution ( 320 ) comprising at least one matrix material and its solvent, iii) subjecting said microneedle template ( 300 ) to a vacuum pressure for a length of time to deprive it of air, iv) dispensing the casting solution ( 320 ) over the air-deprived microneedle template, v) allowing the casting solution ( 320 ) to be drawn into the air-deprived microneedle cavities ( 360 ) completely, and vi) allowing the dissolving microneedles to solidify or dry in a controlled environment.
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