Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 |
filingDate |
2018-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32fcd428641a653b7df4163e57dc565d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d811c4076340b676ca2cf141eab53301 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6d1f4cfe39d01903615cfa9ae90ed17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f3e6abc5705ae9aed77346dc6c7f508 |
publicationDate |
2022-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11498903-B2 |
titleOfInvention |
2-(1,1′-biphenyl)-1H-benzodimidazole derivatives and related compounds as apelin and APJ agonists for treating cardiovascular diseases |
abstract |
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification. The compounds are apelin and APJ agonists for treating cardiovascular diseases. Preferred compounds are 2-(1,1′-biphe-1H-benzo[d]imidazole derivatives. The invention further provides compositions comprising the compounds and the compounds for use in methods of medical treatment. |
priorityDate |
2017-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |