Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4fe47c9fe68e4e9b7181f7995f19d43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate |
2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe075fff7a7930fea5bc4ca930a57174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e576287d1bb3fbb5030d293c88b84d36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29787305569d6497d8fbdd0d387fa5b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50a92e8b44e013b202435a211eb4ced4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fea35f3a0afd25c5f22bbc60d669179a |
publicationDate |
2022-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11474098-B2 |
titleOfInvention |
Drug target for preventing pathologic calcium overload in cardiomyocytes and methods of screening for same |
abstract |
The present invention provides, inter alia, methods for identifying a candidate agent that can treat or ameliorate the effects of a heart condition caused by the effects of abnormal beta-adrenergic receptor activation on calcium levels in cardiomyocytes in a subject. Compositions that include the candidate agents identified by the methods disclosed, and methods of treating or ameliorating the effects of a heart condition in a subject by administering to the subject the candidate agents identified by the methods disclosed, are also provided. |
priorityDate |
2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |