Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-145 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 |
filingDate |
2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9242f7b5fbacd46db43b89a54a2dbbdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a1fb1f009119f657a632e0e6418c35a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69d973b358bbc94fd981879c378ccbde |
publicationDate |
2022-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11440992-B2 |
titleOfInvention |
Oxime cross-linked biocompatible polymer hydrogels and methods of use thereof |
abstract |
Methods and hydrogels for preventing or reducing cellular adhesion and protein adsorption to a tissue (e.g. cardiac tissue) are disclosed. The hydrogels generally include at least three component polymers, a first polymer including an aminooxy group, a second polymer including a reactive oxo group, that are cross-linked by oxime bonds and a third polymer including a catechol group, that causes better retention on the cardiac tissue. The hydrogels are suitable for binding to and coating a tissue or cell. The hydrogels operate to reduce cellular adhesions and protein adsorption to the tissue or cell. |
priorityDate |
2017-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |