http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11407981-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
| filingDate | 2017-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc1713eda4bd5415cb42c800a2465fa7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec8e88f634b7379e143d26db052b9ba4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d8f131384972ebf3be76b11f7c79a0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed72e6b951a570a78898307ffc9e1e47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7b85b56fc539358c31178ec4eacd6d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9957ab6af71ada905464a146f42796a |
| publicationDate | 2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-11407981-B2 |
| titleOfInvention | Methods for continuously inactivating a virus during manufacture of a protein |
| abstract | Methods for continuously inactivating a virus during manufacture of a protein are provided. Steps include (1) combining, at a single predetermined volumetric ratio, a composition including the protein, and a composition including a virus-inactivation reagent, to obtain a treatment composition having a predetermined property for inactivation of a virus; (2) transferring the treatment composition to a treatment vessel; (3) incubating the treatment composition in the treatment vessel at predetermined conditions; and (4) subjecting the treatment composition to a post-treatment processing operation. The single predetermined volumetric ratio has been selected to ensure that the predetermined property of the treatment composition is maintained across a range of concentrations predicted for the protein in the composition including the protein. Steps (1) to (3) are carried out (a) continuously and (b) without feedback control being exerted by either adjustment of the volumetric ratio or diversion of the treatment composition. |
| priorityDate | 2016-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 500.