| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bba5cf7b3c2cc9858dbb1b10065c4f9b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B33Y10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B29C64-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B33Y80-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B29C67-246
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B29C64-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B33Y10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B33Y80-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B29C67-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
| filingDate |
2021-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d75315cbda4b35483db87679f2cd6193
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29e7e04c48dc95f2e132dd48ba033142
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d33d0f38feb2e42c82bf2b993d71ece
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2e2d075eb1399641e99490958e8fdad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f0b678c3e01ce84c46bef4cf1c8436e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b35803e1a3de450db6d9735b723142e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65dd63b9ec904315e404e58a297ceb84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a73572a307ca0370c9ba552329c4e19f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fba8112bd6ef28218abdb9ec3bce3d8 |
| publicationDate |
2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11406732-B2 |
| titleOfInvention |
Tunable, controlled-release, urethane-containing elastomers and processes of forming the same |
| abstract |
A process forms an implantable product including poly(glycerol sebacate) urethane (PGSU) loaded with an active pharmaceutical ingredient (API). The process includes homogeneously mixing a flowable poly(glycerol sebacate) (PGS) resin with the API and a catalyst to form a resin blend. The process also includes homogeneously combining the resin blend with an isocyanate to form a reaction mixture and injecting the reaction mixture to form the PGSU loaded with the API. An implantable product includes a PGSU loaded with an API. In some embodiments, the implantable product includes at least 40% w/w of the API, and the implantable product releases the API by surface degradation of the PGSU at a predetermined release rate for at least three months under physiological conditions. In some embodiments, the PGSU is formed from a PGS reacted with an isocyanate at an isocyanate-to-hydroxyl stoichiometric (crosslinking) ratio in the range of 1:0.25 to 1:1.25. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022257828-A1 |
| priorityDate |
2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |