Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d55dd4da0d8f5bfa72abe0507617311d |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07019 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2020-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd0cc78235ff5bcf0c967418ae96e30f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8d1235717749797ec3af7e990c9e7cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cf7ea3b1e2a8e4647dbfd7ffafb7b6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36e098995518311f4b0b45a86812f3a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_410424c0c699161aa5c85a255f73d3e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a8c711b8cf4fec83019185da37e0f44 |
publicationDate |
2022-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11390862-B2 |
titleOfInvention |
Proteinases with improved properties |
abstract |
Provided herein is a thermolabile proteinase and methods of using the same. In some embodiments, the thermolabile proteinase may comprise an amino acid sequence that is at least 90% identical to any of SEQ ID NOs:1-11 and at least one amino acid substitution in helix 3. The thermolabile proteinase is active at a temperature in the range of 4° C.-40° C. and is inactivated by raising the temperature to above 50° C., where the proteinase is substantially inactive at 65° C. |
priorityDate |
2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |