| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6419
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2201-06113 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6408
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B27-1006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02F1-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-05 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B27-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02F1-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate |
2019-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d8f281e1e7da96fd093d8664948ba3b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4a32072402a7574f82f4b1471d5758b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b20502584e6ff190dbb0441526aa51d2 |
| publicationDate |
2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11371937-B2 |
| titleOfInvention |
Apparatus and methods for fluorescence imaging using radiofrequency-multiplexed excitation |
| abstract |
Apparatus and methods for fluorescence imaging using radiofrequency multiplexed excitation. One apparatus splits an excitation laser beam into two arms of a Mach-Zehnder interferometer. The light in the first beam is frequency shifted by an acousto-optic deflector, which is driven by a phase-engineered radiofrequency comb designed to minimize peak-to-average power ratio. This RF comb generates multiple deflected optical beams possessing a range of output angles and frequency shifts. The second beam is shifted in frequency using an acousto-optic frequency shifter. After combining at a second beam splitter, the two beams are focused to a line on the sample using a conventional laser scanning microscope lens system. The acousto-optic deflectors frequency-encode the simultaneous excitation of an entire row of pixels, which enables detection and de-multiplexing of fluorescence images using a single photomultiplier tube and digital phase-coherent signal recovery techniques. |
| priorityDate |
2013-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |