| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49310188df8dc04b3708491df863459f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A40-146 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8207
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01H1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01H5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8213
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8216 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 |
| filingDate |
2019-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a14e570ace49a1a560326fc2fc8a255
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_479e422d17a5a7d6de46f3e0a8686003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_510ead9a9a5f4249ca2413da6dcbb146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d276ba8d7d9705771ba17b99f1968499
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ac144a71550066d1fdd654621135e5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a88353c56a2ffac1eb29852c85e2eb95 |
| publicationDate |
2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11332752-B2 |
| titleOfInvention |
Use of morphogenic factors for the improvement of gene editing |
| abstract |
Methods and compositions are provided for the improvement of double-strand-break-inducing agent activity in eukaryotic cells, through the usage of one or more morphogenic factors or developmental genes. The morphogenic factor may be provided to the same cell or to a different cell than that comprising or receiving the double-strand-break-inducing agent. The morphogenic factor may be provided to a cell as a polynucleotide composition on a recombinant vector, and may be placed on the vector outside of a T-DNA border. The morphogenic factor may be provided via an upregulation of an endogenous gene. The morphogenic factor, or the double-strand-break-inducing agent, may further comprise a cell penetrating peptide. The morphogenic factor may be co-introduced with a vector comprising RepA. |
| priorityDate |
2018-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |