| abstract |
The present invention relates to TRPV1 modulator compounds of formula (I) or their pharmaceutically, veterinary or cosmetically acceptable salts, or their stereoisomers or mixtures thereof, wherein m is an integer selected from 1 to 3; R 1 , R 2 , R 6 and R 6′ are independently selected from H, (C 1 -C 8 )alkyl, unsaturated (C 2 -C 8 )hydrocarbon, and (C 3 -C 6 )cycloalkyl, being these groups optionally substituted; R 3 is hydrogen or halogen; R 4 is selected from H, (C 1 -C 8 )alkyl, unsaturated (C 2 -C 8 )hydrocarbon, (C 3 -C 6 )cycloalkyl, (C 6 -C 12 )aryl, and (C 5 -C 12 )heteroaryl, being these groups optionally substituted; and R 5 is selected from (C 3 -C 28 )alkyl, unsaturated (C 3 -C 28 )hydrocarbon, (C 6 -C 12 )aryl, and (C 5 -C 12 )heteroaryl, being these groups optionally substituted. It also relates to a process for their preparation, to pharmaceutical, veterinary or cosmetic compositions containing them, and to their pharmaceutical, veterinary and cosmetic applications. |