http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11248038-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6dfc145c8f610fdf1826de1e13ada297 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 |
filingDate | 2020-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_657cc45efe2182d566467c8d3666d659 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_342a6925c1411b6ce781a61f4912214d |
publicationDate | 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-11248038-B2 |
titleOfInvention | Molecular-size of elastin-like polypeptide delivery system for therapeutics modulates intrarenal deposition and bioavailability |
abstract | A renal cortex targeting elastin-like polypeptide (ELP), a renal medulla and cortex targeting ELP, and a method of treating a renal disorder are provided. The renal cortex targeting ELP includes up to 95 repeat units having the sequence VPGXG (SEQ ID NO: 1), where X in each of the repeat units is any amino acid except proline. The renal medulla and cortex targeting ELP includes at least 95 repeat units of SEQ ID NO: 1, where X in each of the repeat units is any amino acid except proline. The method of treating a renal disorder includes administering an ELP and a therapeutic drug to a subject in need thereof, where the ELP includes up to 671 repeat units of SEQ ID NO: 1 and X in each of the repeat units is any amino acid except proline. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020362016-A1 |
priorityDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.