| abstract |
A construct, or a pharmaceutically acceptable salt thereof, comprising:(a) a polyethylene glycol-block-poly(L-lysine) polymer moiety, wherein the polyethylene glycol is thiol-functionalized;(b) a cholecystokinin-B (CCK-B) receptor ligand coupled to the polyethylene glycol of the polymer moiety; and(c) a siRNA complexed with the poly(L-lysine) of the polymer moiety,wherein the construct is neutralized. |