http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11230736-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4cd3dec7f1ed872948bbd19b9aa7a11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6daca7f29ebd36bf83f24a9f6e533058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d33e45e5cbd64b8b893bd62ee22a85b |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
filingDate | 2018-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a961e846cd32671722351319d76d858f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_456cf7404cc96f1335319a3ed04689c3 |
publicationDate | 2022-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-11230736-B2 |
titleOfInvention | Methods for assessing pregnancy outcome |
abstract | The invention relates to a method of assessing pregnancy outcome. The inventors investigated endometrial miRNAs associated with pregnancy outcome by studying miRNAs associated with endometrial receptivity, implantation failure and embryo miscarriage. They performed a miRNomic study to find miRNAs that are differentially expressed according to the endometrial receptivity status, compared the endometrial miRNome between receptive patients with negative beta-hCG and receptive patients with positive beta-hCG, and compared the endometrial miRNome between receptive patients with a miscarriage between 8-12 weeks of amenorrhoea and receptive patients with a live birth. They demonstrated miRNA differential expression in endometrial samples according to the pregnancy outcome. Thus, the invention relates to a method of assessing pregnancy outcome of a patient, comprising a step of measuring in a biological sample obtained from the patient the expression level of at least one miRNA selected from the group consisting of miR-455-3 p, miR-4423-3p, miR-4445-3p, miR-3128, miR-3201, let-7b-5p, let-7c-5p, miR-4534, miR-214-3p, miR-15b-5p, miR-424-3p, miR-181a-5p, miR-574-3p, miR-92a-3 p, miR-320c, let-7d-5p, miR-125a-5p, miR-320a, miR-320b and let-7f-5p. |
priorityDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 260.