| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d9fd632e7ef936d0d33e7b9b5f018c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-922
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4893 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-28 |
| filingDate |
2018-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3e88760fb681b500ee9871dcb388eb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af7ba2466e4e9e0945b1b0870aa7eff7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_328872a704f4f8be323c26d950fb4b8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a1220d8e25a9741b4b69e54d001b6b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8baf732a7f3c0f04c3a676ba724eab2 |
| publicationDate |
2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11224564-B2 |
| titleOfInvention |
Composition comprising erigeron annuus flower essential oil for prevention and treatment of neuromuscular disease |
| abstract |
Disclosed are a pharmaceutical composition and a beauty-purposed pharmaceutical composition for prevention or treatment of neuromuscular disease, the composition including a combination of Erigeron annuus flower-based essential oil and Botox. Erigeron annuus flower-based essential oil inhibits t-SNARE protein and v-SNARE protein expression in neurons to inhibit the formation of SNARE protein complexes. Erigeron annuus flower-based essential oil inhibits the regeneration of t-SNARE protein and v-SNARE protein degraded by Botox to inhibit neurotransmitter release. Accordingly, an efficacy duration of Botox may be extended. Thus, Erigeron annuus flower-based essential oil may be usefully used in combination with Botox as Botox adjuvant for the prevention and treatment of neuromuscular disease or for beauty. |
| priorityDate |
2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |