Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ffd5528fd07384d7b07ab484ed5b143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 |
filingDate |
2018-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b1993c9a106e931fd0c0994cbac4314 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_000c1bfe05e0e7ccdb584784c987a0b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_886532fe7f86d760f9eed1300040493b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09bcf5ba4d631b976c410ed3cb08fe7a |
publicationDate |
2022-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11213518-B2 |
titleOfInvention |
Ligands of the mu, kappa, and delta opioid receptors |
abstract |
Ligands of the mu, kappa, and delta opioid receptors and methods of using them are disclosed. In particular, the invention relates to the discovery of new opioid receptor ligands based on molecular dynamics simulations of conformational states of the μ opioid receptor and the use of the identified opioid receptor ligands as analgesics, anti-diarrheal agents, and overdose reversal agents. |
priorityDate |
2017-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |