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filingDate 2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_795bdc5f897cedc58b66be4521f6b936
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publicationDate 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11199549-B2
titleOfInvention MEl'hods and means for diagnosing spondylarthritis using autoantibody markers
abstract The present invention relates generally to methods for diagnosing the presence or the risk of development or the therapy control of spondyloarthritis (Spa), in particular, of ankylosing spondylitis (AS) and undifferentiated spondyloarthritis in a subject, in particular in mammals. In addition, the present invention relates to test kits for use in the diaposis of the presence or the risk of development, or for the therapy control of Spa, like AS and undifferentiated spondyloarthritis, in a subject. In particular, the present invention relates to a method for diagnosing the presence or the risk of development, or for the therapy control of Spa, like AS and undifferentiated spondyloarthritis, it a subject analysing for the presence of autoantibodies against CD74 and/or IKBKB in a subject. The presence of autoantibodies against CD74 and/or IKBKB is indicative for the presence or the risk of development, or for the therapy control of Spa, like AS and undifferentiated spondyloarthritis. In particular, detection of the presence of autoantibodies against CD74 and/or IKBKB allows early diagnostic of Spa, in particular, AS and undifferentiated spondyloarthritis.
priorityDate 2010-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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